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Hey Viagra users! Do you know how your magic pill works on you? Hmmm…forgotten right! Or are you ignorant about its mechanism? Whatever, am sure about one thing you were startled after reading the title of this write-up! To understand Viagra mechanism we need to first understand how one gets a penis erection. Penile erection process is initiated with sexual excitement. The stimulation generates electrical impulses in the brain and sends it to the nerves going to the penile section. The nerve then releases nitric oxide to increase the production of cyclic GMP in muscle cells of corpus cavernosum simultaneously. Nitric oxide smoothes the muscles and increases the size of the blood vessels allowing high-speed blood flow to the penis. As a result the penis is engorged with blood making it firm and strong for penetrative sex. So what we understand from this is that the level of NO (Nitric oxide) is mainly responsible for giving a strong penile erection. Viagra does not have any direct relaxant effect on the penile section but it enhances the effect of nitric oxide by inhibiting phosphodiesterase type 5 (PDE5). When sexual stimulation leads to the release of Nitric oxide, the inhibition of PDE5 by Viagra causes increased levels of cyclic guanosine monophosphate which gives muscle relaxation and blood inflow to the corpus cavernosum which ultimately helps in getting the required erections of the penis. Now, I am sure you will be able to relate the Nobel Prize winner Dr. Furchgott with Viagra and its functioning. Nitric oxide was initially known as Endothelial Derived Relaxing Factor (EDRF), ERDF was released, when patients took the nitrate-type blood pressure medicines popular in the 1970s and 1980s, and in turn it caused relaxation of the smooth muscles around the blood vessels and the arteries became larger, allowing better blood flow and a lower blood pressure. In 1986, Dr. Furchgott identified the EDRF as nitric oxide. This is where the Viagra makers got the idea of a magic pill for sex which revolutionized the whole idea of impotence. They noticed from the research that the nitrate drugs had certain side-effects on the blood vessels and the arteries; relaxing the smooth muscles around the blood vessels thereby increasing the blood flows in the human body. They related it to the erectile anatomy and discovered Sildenafil citrate, a chemical that inhibited PDE5 inhibitors which is responsible for the level of NO (nitric oxide) in the penile section. Sildenafil Citrate, under the brand name of Viagra, became the pioneer pill for the treatment of erectile dysfunction and received FDA approval on March 27, 1998, the rest is history! After all a better blood flow is the key factor behind a strong erection. So the master mind behind Viagra, in a way, remains Dr. Furchgott, the inventor of nitric oxide. Without the knowledge of the existence of nitric oxide, no one could think of inhibiting phosphodiesterase type 5 to maintain the level of NO to get penis erection. Let’s toast for the good health of Dr. Furchgott and congratulate him on winning the Nobel Prize. Without his discoveries Viagra would not have been possible and millions of men with erectile dysfunction would have continued to live hopelessly and helplessly as ‘ashamed impotents’. Thanks Dr. Furchgott for everything you have given us through your discovery! best enargement exercise penis real penis enlagement herbal penis enlagement free penis enargement vigrx pic penis enargement information does penile enlargement work cheap penile enlargment pills

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As a diabetic, you are at a constant risk of developing complications. What are these complications? What are their symptoms? Which body part is most affected? Let’s have the answers to these questions. Blood Vessels Diabetes could harm your small blood vessels. The small vessels include those in your eyes, kidneys, and nerves. The larger ones include those in your heart and lower legs. Kidney Kidney damage is very common in diabetes. The disease varies with each patient and the rate of its progress. Diabetic nephropathy occurs when your small blood vessels present in your kidneys get damaged. This leads to a leak of protein into your urine. As a result, your kidneys lose their ability to filter your blood. At times, dialysis may be required to flush out the toxins from your blood. In extreme cases, you may require a kidney transplant. Nerves Nerve damage can lead to a complete loss of sensation in your feet. Sometimes, the reverse happens. You feel constant pain in your feet. It becomes difficult to wear shoes or sandals. Even a small wound can develop into a serious infection, rotting ulcers, gangrene, and even amputation of the affected part. In men, nerve damage may lead to impotence. Diabetic neuropathy affects the nerves connecting to the penis, thus, not letting the penis get an erection. If the penis does not get the required amount of blood flow, it may lead to erectile dysfunction. Eyes Your eyes are other organs to get affected. It is called diabetic retinopathy and it usually occurs in patients suffering from diabetes for as long as five years. The damage of blood vessels located at the back of your eye leads to a leakage of protein as well as blood into the retina. It also causes small aneurysms. The new blood vessels develop but are brittle. There might be bleeding from the newly developed blood vessels, which may lead to scarring, and your retina may get detached resulting in a damaged eyesight. These complications are scary enough to make you sit up and take notice. Well, they are dangerous enough to take your life too! So, start caring for your body today! penis enlagement tip permanent penis enlargement surgical pennis enlargement penis enlagement excersizes penile enlargement device do penile enlargment pills work free natural penis enlagement penis elargement before and after penis enlagement without pills

What Is Nitric Oxide (NO)? Nitric oxide (NO) is produced by healthy endothelial cells. The discovery of its function is possibly one of the most important in the history of cardiovascular medicine. In 1998 three Americans (Robert F. Furchgott, PhD, Louis J. Ignarro, PhD, and Ferid Murad, MD, PhD) were awarded the Nobel Prize for their independent discoveries concerning "nitric oxide" as a signaling molecule in the cardiovascular system. Nitric oxide (NO) is essentially a signaling molecule that helps control a range of processes in the body, including nerve signaling, immune functions, muscle growth and the dilation of blood vessels. Nitric Oxide (NO) And Increased Positive Blood Flow Since the discovery that Nitric oxide (NO) is able to induce vasodilation a large number of other roles have been described for Nitric oxide (NO). It is also known to play a role in the immune system, the nervous system, in inflammation and in programmed cell death (apoptosis). Nitric oxide (NO) has also been implicated in smooth muscle relaxation, pregnancy and blood vessel formation (angiogenesis). Viagra and Nitroxagen Increase Nitric Oxide (NO) Levels Scientists have also taken this Nitric oxide (NO) research and run with it for commercial applications. Probably the best known is Viagra. The drug increases the levels of Nitric oxide (NO) and promotes smooth muscle relaxation. This, in turn, allows for extra blood flow to the penis, leading to erection. For fitness minded individuals, Nitroxagen is probably the most effective (NO) related product. Nitroxagen is an apple-flavored Nitric Oxide (NO) powder that has the ability to create a natural "muscle pump" that remains in a post-exercise state. Like Viagra, Nitroxagen is also being used to treat sexual dysfunction in men who have difficulty in maintaining an erection. Researchers are continuing to study the possible uses of nitric oxide and its link to heart disease prevention and other assorted medicinal uses. In the meantime, scientists recommend that you maximize Nitric oxide (NO) production in your body by following a low fat diet, getting some exercise, consuming antioxidants like vitamins A and C, which prevent the breakdown (oxidation) of nitric oxide in the body. free penis enargement pills penis enargement tool cheap penile enlargment herbal natural penis enlarement penis enlargment pills review best penis enlargment free penile enlargment exercise penis enargement forum penis enlagement without pills

Yes, by all means, but it is technically called hypogonadism (low testosterone levels). Symptoms may vary, but most men will experience decreased libido (sexual desire) as well as erectile dysfunction, hot sweats, decrease in body hair, fatigue, or even depression. They also tend to lose muscle mass and gain weight due to increased subcutaneous fat. Erectile dysfunction is a common complaint of male patients past the age of 50, and although it is most commonly caused by such problems as vascular insufficiency (decreased blood flow) to the penis which usually responds well to such medications as Viagra, Cialis, or Levitra, your physician should check for hypogonadism as a possible cause and also screen for cardiovascular disease as well as diabetes. Certain prescription medications can also lead to problems with both libido and sexual dysfunction; most notably certain anti-depressants and hypertensive medications. Serum testosterone levels are at their highest between the ages of 20 to 30 and tend to progressively fall after age 40. If your testosterone levels come back low, your physician may wish to order a couple of other tests to determine the actual cause. There are other causes of low testosterone other than merely aging. If your testosterone level IS low and you are going to receive treatment, make sure that you are screened for prostate cancer. Your doctor should perform a digital rectal exam, order a PSA (prostate specific antigen) blood test, and your testicles should be examined for size, nodules and other abnormalities. Topical testosterone gel is usually the preferred method of administering the hormone. Topical 1% testosterone is available as Androgel or Testim. The starting dosage is 5 gm a day and applied to dry skin of the abdomen, upper arm or shoulders. The gel should not be placed on the genitals! The area of skin should be allowed to dry and a shirt be worn during contact with children or women as it IS possible to transfer the medicine to the skin of another individual. The serum testosterone level should be determined again about two weeks after initiating treatment. The administration of testosterone replacements have NOT been demonstrated to increase the incidence of prostate cancer, myocardial infarction, cardiovascular disease, or stroke. It can, however, elevate the PSA (prostate specific antigen) level. Treament has come a long way over the past few years with the advent of the topical applications. Testosterone used to be given by intramuscular injection which was both painful and had to be given rather frequently because the levels of the medication would not last long in the blood stream. The topical applications tend to maintain an even level of medication at all times without the peaks and valleys caused by the old injections. Testosterone replacement should improve libido, muscle mass, and well being. It can aggravate sleep apnea, cause mild acne, and gynecomastia (slight enlargement of the breasts), but NOT in everyone. It can enable a male to feel much more vibrant, improve his sexual desire, ability, and performance, and make life a lot more enjoyable overall. Copyright 2006 Ted Crawford herbal natural penis enlarement penis enhancement before and after picture homemade penis enlargment top penis elargement pills pennis enlargement operation free penile enlargement video natural pennis enlargement technique penile enlargment video penis enlagement without pills

Increased sexual pleasure has been a goal common to both men and women throughout history. However, achieving such a goal is not always as easy as one would like to think. While we commonly see depictions of intensely sensual sexual activities, hear about climatic orgasmic experiences, and can read about extremely long love-making sessions; bringing this flavor of enjoyment into our actual lives is not always easy as these media outlets make it seem. Some men might have problems achieving a hard erection and women often find they have a decreased sexual appetite. What them, can be done to achieve the type of sexual experiences that we currently only fantasize about? After intense research into this dilemma, it has been discovered that the intake of a high level of amino acids is of great assistance to redeveloping sexual desire and performance. For men, amino acids work to escalate the amount of ejaculation fluid which results not only in increased sperm count, but also greatly amplifies the sexual experience through prolonged orgasms. Not only is the penis able to increase in size and hardness, but stamina and desire is magnified. For women, amino acids allow a larger amount of blood to flow into their clitoris and vaginal tissues. This results in heightened sensitivity, which encourages sexual desire and activity. In addition, when a woman is taking amino acid supplements, her orgasms are extremely enhanced, leading to a drastic increase in sexual pleasure. One of the most popular amino acids on the market is L-Arginine, a semi-essential amino acid. It has been proven to create increased blood flow to the sexual organs of both men and women. L-Arginine is described as a free-form amino acid, one that is crystalline. Not only has L-Arginine been shown to improve sexual quality and performance, it is also known to work in relocating nitrogen throughout the body. It is also highly important to the body’s metabolism and is known to be beneficial to the activity of the blood vessels surrounding the heart. L-Arginine can be found in numerous sexual enhancement products. When looking for an L-Arginine supplement, try to find one that uses natural herbs in addition to high levels of amino acids. The combination results in increased stimulus for women, and penis enlargement and increased fluid ejaculation for men. In addition, L-Arginine has been proven to aid the body in many other ways, such as lowering blood pressure levels and is an overall healthy supplement to one’s health regime.